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Parkinson's Disease

Parkinson’s Disease Stem Cells Therapy at Swiss Medica Clinic

Parkinson's disease is a chronic degenerative disease of the nervous system, in which person loses movement control ability. The disease develops relatively slowly, but has a progression tendency. It is a fairly common problem – 4% of the elderly population suffering from Parkinson's disease manifestations. It is known that Parkinson's disease occurs due to dopamine (one of the neurotransmitters, substances that are used to transmit brain impulses) production violation. This leads to dysfunction of the movement-responsible cells which are located in the brain regions. Predisposition to the disease can be inherited.

Some of Parkinson's disease symptoms may be caused by other factors, such as encephalitis, excessive medication, cerebral atherosclerosis or poisoning neurotoxic substances. And if earlier, none of the methods give the expected results, today the development of stem cells therapy make possible to slow down or even eliminate the disease and its consequences. Stem cells therapy for Parkinson's disease is the only really effective method of dealing with Parkinson's. But let's first look at what's going on in the disease process.

What the appearance of the disease is accompanied by?

The appearance of the first disease symptoms usually goes unnoticed. Often person’s relatives and friends pay attention to the face expression decrease, lowness of movement, especially when dressing, eating and walking. Subsequently, the patient himself notes the decrease of manual dexterity, especially when performing fine movements. There are also writing breaches, the difficulties with teeth brushing, shaving and so on. The person rarely blinks, one’s face become mask-like. Person becomes unable to walk, but easily runs up the stairs, dance or skiing. Slow movement can be suddenly changed with fast running, which patient cannot overcome until the fall or confronted with barriers. Turns in bed are also much more difficult as well as getting out of a chair or stool. Due to pharynx muscles mobility violations, swallowing movements become rare and causes the salivation development. The latter can be so intense that a person is forced to use a handkerchief or towel. Compulsory Parkinson's disease symptoms are stiffness (hypokinesia), tremor occurring and problems with walking.

Causes of disease

The causes of Parkinson's disease are not yet fully understood. Scientists have put forward many theories. Some of them we now consider:

  • Damage to the cells of the substantia nigra by free radicals. These particles interacting with the molecules of the brain take over one electron and cause their oxidation.
  • Brain tissues damage under different external toxins poisoning. Internal toxins that are caused by kidneys and liver violation subsequently cause symptoms of Parkinson's disease.
  • Heredity is also considered as a reason which increases the risk of disease. For example, 20% of patients have relatives with symptoms of Parkinson's disease.
  • The presence of altered gene. Geneticists have identified several genes, the presence of which causes a Parkinson's disease at a young age.
  • Vitamin D deficiency, which is formed in the body under the influence of sunlight. Within years the body loses this ability and the risk of disease increases. Vitamin D protects brain cells from the effects of toxins and free radicals. Therefore, in adulthood patient must provide vitamin D intake by eating fish and cereals.
  • The occurrence of defective mitochondrial mutation. They occur in brain neurons and lead to the degeneration of these cells.
  • Encephalitis of viral and bacterial origin. Different brain tissue inflammation leads to the emergence of Parkinson's disease.
  • Atherosclerosis and other vascular diseases.
  • Traumatic brain injury. Particularly repeated concussions can cause the substantia nigra cells’ disruptions.

Parkinson’s disease symptoms

The disease develops gradually. The majority of patients are people have stepped 50-year age. In the initial stages the symptoms are virtually absent, and disease identification can only be a result of deep examination. Gradually, the disease progresses, and the number of affected cells also increase. So the symptoms become more pronounced. Changes lead to disability and complete immobilization. Seriously ill patients often have only 20% of substantia nigra operable cells.

The first signs of Parkinson's disease

  • Weakness, fatigue and general malaise.
  • Shaky, short and uncertain gait.
  • Nasal speak, thought forgetting.
  • Change of writing skills. Letters become smaller, angular and "trembling".
  • Mood swings and depression periods.
  • Unemotional mimicry.
  • Muscles rigidity (significantly increased muscle tone).
  • Tremor (fast rhythmic muscle movements). At first, 70% of patient’s tremor observed on one hand. Over the time, muscle contraction applies to all limbs.

Early stem cell therapy for Parkinson's disease with the use of adult autologous stem cell helps to achieve the best results. But in the most severe cases, therapy with mesenchymal stem cells can be effective as well.

If you are unable to diagnose the disease in time, it is likely that you will encounter a number of the following consequences:

  • Quick tiredness and weakness.
  • Mask-like face.
  • Steady hand and feet bent condition. When you try to straighten the patient’s arm, a "gear phenomenon" (intermittent character of movement) occurs.
  • Limbs tremor. It has specific character: finger movements resemble recounting coins or rolling a ball. Trembling can be observed not only in hands, but it also affects foot and lower jaw. The symptom may be observed as stress and at rest and it disappears during sleep.
  • Bradykinesia (sharp of slow motion). Washing, dressing and other daily activities can take several hours.
  • Strong stoop.
  • Muscles pain caused by the constant contraction and spasm.
  • Coordination violations, unsteady gait, frequent falls.
  • Difficulty to maintain one certain position.
  • Severe chronic depression and periods of torpor. Timidity and diffidence, fear of public events, motivation lost, memory impairment.

It is worth noting that the course of the disease is individual for each person. Therefore, some symptoms may predominate while others expressed weakly. Parkinson's disease is a serious disease that can greatly complicate patient’s life. The causes leading to the appearance of Parkinson's disease are very diverse. Among them is a hereditary tendency, age-related changes, environmental influences. None of us is immune from it.

Parkinson’s disease Stem Cells Therapy at Swiss Medica

For the first time the results of Parkinson's disease and stem cell therapy was published in 2009. According to obtained data, after 36 months after the stem cells introduction, positive effect was observed in 80% of patients. Today more people know about stem cell therapy, and the number of patients SwissMedica XXI century is growing. And this growth is not a consequence of the disease spread of, but a consequence of the treatment effectiveness.

Mesenchymal stem cell therapy is helpful for each patient, the only difference is the degree of effect. Parkinson's disease treatment – is the implantation of patient's own stem cells into the brain. Healthy cells formation processes predominate over the decomposition processes, thus recovery occurs.

Our stem cell therapy clinic guarantees:

  • Effective stem cell Parkinson’s disease treatment.
  • Long-term follow-up (at least for 6 month).
  • Impossibility of contamination by transmissible illnesses.
  • The short period of time between making lipo-aspiration and injecting the activated stem cells to the patient.
  • Absence of rejection.
  • Absence of oncological complications.
  • Assistance of highly qualified professionals.
  • Top treatment standards for every patient.

SwissMedica Parkinson’s disease mesenchymal stem cells treatment available in Luсerne, Moscow and Belgrade.